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Article

High-efficiency EGFR genotyping using cell-free DNA in bronchial washing fluid.

Japanese journal of clinical oncology - 1 Jun 2024

Murata Yoshihiko, Nakajima Yumi, Sato Yukio, Hizawa Nobuyuki, Yamakawa Daichi, Matsubara Daisuke, Noguchi Masayuki, Minami Yuko

Abstract excerpt

BACKGROUND: EGFR mutation testing is required for treatment of lung adenocarcinoma using epidermal growth factor receptor-tyrosine kinase inhibitor. However, the amounts of tumor tissue or tumor cells obtained by bronchoscopy are often insufficient. Bronchial washing fluid, obtained by lavage with saline after tumor biopsy or brushing, and the supernatant of bronchial washing fluid are thought to contain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38476004
DOI: 10.1093/jjco/hyae021
PMCID: PMC11144292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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