Article
Compared to plasma, bronchial washing fluid shows higher diagnostic yields for detecting EGFR-TKI sensitizing mutations by ddPCR in lung cancer.
Respiratory research - 9 Jun 2020
Lee Sang Hoon, Kim Eun Young, Kim Taehee, Chang Yoon Soo
Abstract excerpt
BACKGROUND: The rate of diagnosis of advanced lung adenocarcinoma must be improved. In this study, we compared the detection rates of EGFR-tyrosine kinase inhibitor-sensitizing mutations (mEGFRs) in bronchial washing fluid (BWF) and the plasma of patients with lung adenocarcinoma using the tissue genotype as the standard reference. METHODS: Paired blood and BWF specimens were collected from 73 patients with lung...
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