Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The fitness trade-off between growth and stress resistance determines the phenotypic landscape.

BMC biology - 13 Mar 2024

Kim Dongsan, Hwang Chae Young, Cho Kwang-Hyun

Abstract excerpt

BACKGROUND: A central challenge in biology is to discover a principle that determines individual phenotypic differences within a species. The growth rate is particularly important for a unicellular organism, and the growth rate under a certain condition is negatively associated with that of another condition, termed fitness trade-off. Therefore, there should exist a common molecular mechanism that regulates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Biological Evolution
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 38475791
DOI: 10.1186/s12915-024-01856-7
PMCID: PMC10935846

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The fitness trade-off between growth and stress resistance determines the phenotypic landscape.PMID 38475791Read ↗

Hunger artists: yeast adapted to carbon limitation show trade-offs under carbon sufficiency.Semantic proximity Read ↗

The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast.Semantic proximity Read ↗

Stress, genomic adaptation, and the evolutionary trade-offSemantic proximity Read ↗

Shaping of microbial phenotypes by trade-offs.Semantic proximity Read ↗

Genome-wide analysis of yeast stress survival and tolerance acquisition to analyze the central trade-off between growth rate and cellular robustness.Semantic proximity Read ↗

Drug-dependent growth curve reshaping reveals mechanisms of antifungal resistance in Saccharomyces cerevisiaeSemantic proximity Read ↗

Differential regulation of antagonistic pleiotropy in synthetic and natural populations suggests its role in adaptation.Semantic proximity Read ↗

Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data.Semantic proximity Read ↗

Understanding the adaptive laboratory evolution of multiple stress-resistant yeast strains by genome-scale modeling.Semantic proximity Read ↗

The cost of gene expression underlies a fitness trade-off in yeast.Semantic proximity Read ↗

Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant.Semantic proximity Read ↗

The Fitness Cost of Therapeutic Resistance in Cancer: A Systematic ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.