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Article

Unravelling the Intricate Roles of FAM111A and FAM111B: From Protease-Mediated Cellular Processes to Disease Implications.

International journal of molecular sciences - 29 Feb 2024

Naicker Danielle, Rhoda Cenza, Sunda Falone, Arowolo Afolake

Abstract excerpt

Proteases are critical enzymes in cellular processes which regulate intricate events like cellular proliferation, differentiation and apoptosis. This review highlights the multifaceted roles of the serine proteases FAM111A and FAM111B, exploring their impact on cellular functions and diseases. FAM111A is implicated in DNA replication and replication fork protection, thereby maintaining genome integrity....

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Identifiers

PMID: 38474092
DOI: 10.3390/ijms25052845
PMCID: PMC10931937

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Unravelling the Intricate Roles of FAM111A and FAM111B: From Protease-Mediated Cellular Processes to Disease Implications.PMID 38474092Read ↗

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