Article
Obesity risk in young adults from the Jerusalem Perinatal Study (JPS): the contribution of polygenic risk and early life exposure.
International journal of obesity (2005) - 1 Jul 2024
Hochner Hagit, Butterman Rachely, Margaliot Ido, Friedlander Yechiel, Linial Michal
Abstract excerpt
BACKGROUND/OBJECTIVES: The effects of early life exposures on offspring life-course health are well established. This study assessed whether adding early socio-demographic and perinatal variables to a model based on polygenic risk score (PRS) improves prediction of obesity risk. METHODS: We used the Jerusalem Perinatal study (JPS) with data at birth and body mass index (BMI) and waist circumference (WC) measured...
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