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Can Endometrial Cytology Identify Patients Who Would Benefit from Immunotherapy?

Acta cytologica - 1 Jan 2024

Yanazume Shintaro, Kirita Yukari, Kobayashi Yusuke, Kitazono Ikumi, Akahane Toshiaki, Mizuno Mika, Togami Shinichi, Tanimoto Akihide, Kobayashi Hiroaki

Abstract excerpt

INTRODUCTION: Patients with polymerase epsilon (POLE) mutation (POLEmut) subtype, MMR-deficient (MMR-d) subtype as classified by The Cancer Genome Atlas (TCGA), and a high tumor mutation burden (TMB-high) potentially benefit from immunotherapy. However, characteristics of the cytological morphology within these populations remain unknown. METHODS: DNA extracted from formalin-fixed paraffin-embedded tissues was...

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PMID: 38471464
DOI: 10.1159/000538288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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