Article
Association of the MSX2 gene polymorphisms with ankylosing spondylitis in Japanese.
Journal of human genetics - 1 Jan 2008
Furuichi Tatsuya, Maeda Koichi, Chou Chung-Tei, Liu Yu-Fen, Liu Ting-Chun, Miyamoto Yoshinari, Takahashi Atsushi, Mori Kanji, Ikari Katsunori, Kamatani Naoyuki, Kurosawa Hisashi, Inoue Hisashi, Tsai Shih-Feng, Ikegawa Shiro
Abstract excerpt
Several genes have been implicated in the etiology of ankylosing spondylitis (AS); however, the significance of these genes except HLA-B27 remains to be elucidated. In this study, we examined the association of AS with novel candidate genes and previously reported genes other than HLA-B27. We examined a total of 45 single nucleotide polymorphisms (SNPs) in 15 genes by a sequential screening. We first genotyped...
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