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Article

The interaction between polygenic risk score and trauma affects the likelihood of post-traumatic stress disorder in female victims of sexual assault.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Jan 2024

Bugiga Amanda Victória Gomes, Carvalho Carolina Muniz, Oliveira Adrielle Martins, Coimbra Bruno Messina, Chehimi Samar Nasser, Zanardo Evelin Aline, Kulikowski Leslie Domenici, Mello Andrea Feijó, Ota Vanessa Kiyomi, Mello Marcelo Feijo, Belangero Sintia Iole

Abstract excerpt

OBJECTIVE: Post-traumatic stress disorder (PTSD) is triggered by traumatic events, but genetic vulnerability and a history of childhood trauma may also increase the risk of PTSD onset. Thus, we investigated the interaction between genetic susceptibility according to polygenic risk score (PRS), and traumatic events. METHODS: We evaluated 68 women with PTSD who had been sexually assaulted and 63 healthy controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38467473
DOI: 10.47626/1516-4446-2023-3335
PMCID: PMC11474442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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