Article
Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging.
Genetics - 1 Sept 2000
Yuan D S
Abstract excerpt
The biochemistry of human nutritional zinc deficiency remains poorly defined. To characterize in genetic terms how cells respond to zinc deprivation, zinc-regulated genes (ZRG's) were identified in yeast. Gene expression was probed using random lacZ reporter gene fusions, integrated by transposon tagging into a diploid genome as previously described. About half of the genome was examined. Cells exhibiting...
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