Article
Regulation of zinc homeostasis in yeast by binding of the ZAP1 transcriptional activator to zinc-responsive promoter elements.
The Journal of biological chemistry - 30 Oct 1998
Zhao H, Butler E, Rodgers J, Spizzo T, Duesterhoeft S, Eide D
Abstract excerpt
Zinc homeostasis in yeast is controlled primarily through the regulation of zinc uptake. Transcription of the ZRT1 and ZRT2 zinc transporters increases in zinc-limited cells, and this induction is dependent on the ZAP1 gene. We hypothesized previously that ZAP1 encodes a zinc-responsive transcrip...
Topics
- Alleles
- Base Sequence
- DNA Primers
- Gene Expression Regulation
- Homeostasis
- Promoter Regions, Genetic
- Saccharomyces cerevisiae Proteins
- Signal Transduction
- Trans-Activators
- Transcription Factors
- Zinc