Article
Maternal and Offspring Fatty Acid Desaturase Variants, Prenatal DHA Supplementation, and Dietary n-6:n-3 Fatty Acid Ratio in Relation to Cardiometabolic Health in Mexican Children.
The Journal of nutrition - 1 May 2024
Wimalasena Sonia Tandon, Ramírez Silva Claudia Ivonne, Gonzalez Casanova Ines, Rivera Juan A, Sun Yan V, Stein Aryeh D, Ferranti Erin P, Alvarez Jessica A, Demmelmair Hans, Koletzko Berthold, Ramakrishnan Usha
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) in fatty acid desaturase (FADS) genes may modify dietary fatty acid requirements and influence cardiometabolic health (CMH). OBJECTIVES: We evaluated the role of selected variants in maternal and offspring FADS genes on offspring CMH at the age of 11 y and assessed interactions of genotype with diet quality and prenatal docosahexaenoic acid (DHA) supplementation....
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