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[FLT3-ITD mutation-positive acute myeloid leukemia undergoing clonal transition with PTPN11 mutation at relapse].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2024

Kurihara Kazuya, Sadato Daichi, Najima Yuho, Hirama Chizuko, Haraguchi Kyoko, Kato Kana, Kondo Kaori, Sadaga Yasutaka, Kato Chika, Sakai Satoshi, Kambara Yasuhiro, Nabe Yoshimi, Teshima Koh, Asano Kazuya, Jinguji Atsushi, Shimabukuro Masashi, Ouchi Fumihiko, Inai Kazuki, Koi Satoshi, Shingai Naoki, Toya Takashi, Shimizu Hiroaki, Kobayashi Takeshi, Oboki Keisuke, Harada Hironori, Okuyama Yoshiki, Harada Yuka, Doki Noriko

Abstract excerpt

A 28-year-old man was diagnosed with acute myelomonocytic leukemia. He achieved complete remission (CR) after two cycles of induction therapy. However, after consolidation therapy, bone marrow aspiration performed to prepare for allogeneic hematopoietic stem cell transplantation revealed disease relapse. Companion diagnostics confirmed the presence of the FLT3-ITD mutation. The patient received gilteritinib...

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Identifiers

PMID: 38447999
DOI: 10.11406/rinketsu.65.63

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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