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Clinical features and management of germline CEBPA-mutated carriers.

Leukemia research - 1 Mar 2024

Pan Lili, Li Yining, Gao Huiying, Lai Xiaolin, Cai Yuanhua, Chen Zhixiang, Li Xiaofan, Wang Shao-Yuan

Abstract excerpt

Familial acute myeloid leukemia (AML) pedigrees with germline CCAAT/enhancer-binding protein-α (CEBPA) mutation have been rarely reported due to insufficient knowledge of their clinical features. Here, we report two Chinese families with multiple AML cases carrying germline CEBPA mutations, one of which had 11 cases spanning four consecutive generations. Additionally, we collected clinical data of 57 AML patients...

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Identifiers

PMID: 38442594
DOI: 10.1016/j.leukres.2024.107453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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