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CRISPR/Cas13a-based single-nucleotide polymorphism detection for reliable determination of ABO blood group genotypes.

The Analyst - 25 Mar 2024

Wei Hongjuan, Liu Liyan, Jiang Hanji, Chen Hong, Wang Yunxiang, Han Yongjun, Rong Zhen, Wang Shengqi

Abstract excerpt

The ABO blood group plays an important role in blood transfusion, linkage analysis, individual identification, etc. Serologic methods of blood typing are gold standards for the time being, which require stable typing antisera and fresh blood samples and are labor intensive. At present, reliable determination of ABO blood group genotypes based on single-nucleotide polymorphisms (SNPs) among A, B, and O alleles...

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Identifiers

PMID: 38441624
DOI: 10.1039/d3an02248j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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