Article
Impact of Tumor Grade Distribution on Genetic Alterations in Clear Cell Renal Cell Carcinoma and Prostate Cancer.
Cancer genomics & proteomics - 1 Jan 2000
Mizutani Kosuke, Sugiyama Seiji, Kameyama Koji, Kamei Shingo, Yokoi Shigeaki, Morikawa Akemi, Takeuchi Makoto, Seike Kensaku, Yamada Toru, Ehara Hidetoshi, Sawada Seiya, Hirade Kouseki, Furuta Hirohito, Matsunaga Kengo, Yamada Tetsuya, Sakamoto Ippei, Kato Yasutaka, Nishihara Hiroshi, Ishihara Satoshi, Deguchi Takashi
Abstract excerpt
BACKGROUND/AIM: A genomic analysis based on next-generation sequencing is important for deciding cancer treatment strategies. Cancer tissue sometimes displays intratumor heterogeneity and a pathologic specimen may contain more than two tumor grades. Although tumor grades are very important for the cancer prognosis, the impact of higher tumor grade distribution in a specimen used for a genomic analysis is unknown....
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