Article
Distribution and Clinical Significance of Hepatitis B virus A1762T/G1764A Double Mutation in Chronic Hepatitis B Patients: A Cross-Sectional Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Feb 2024
Changsri Khaimuk, Duangchanda Thitimonrat, Soimanee Thanawan, Fuckpo Waraporn, Pipatsatitpong Duangnate, Akekawatchai Chareeporn
Abstract excerpt
BACKGROUND: Chronic hepatitis B (CHB) is well-known as a major risk for liver cirrhosis and hepatocellular carcinoma (HCC). The A1762T/G1764A double mutation in the hepatitis B virus genome affects the production of HBe antigen and is established as a predictive marker for progression to HCC. Thus, this study aimed to investigate the prevalence and clinical significance of the mutation in Thai CHB patients....
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