Article
Identification of hepatitis B virus A1762T/G1764A double mutant strain in patients in Southern Brazil.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Silva Souza Adaliany Cecília da, Souza Marasca Giórgia de, Kretzmann-Filho Nélson Alexandre, Dall-Bello Aline, Alexandre Kliemann Dimas, Valle Tovo Cristiane, Gorini da Veiga Ana Beatriz
Abstract excerpt
Infection by hepatitis B virus (HBV) is a worldwide public health problem. Chronic HBV infection with high viral replication may lead to cirrhosis and/or hepatocellular carcinoma. Mutant HBV strains, such as the HBV A1762T/G1764A double mutant, have been associated with poor prognosis and higher risk of the patient for developing cirrhosis and/or hepatocellular carcinoma. This study analyzed the presence of the...
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