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Association between leisure sedentary behaviors and hypertension risk: A prospective cohort study and two-sample Mendelian randomization analysis in Europeans.

Preventive medicine - 1 Apr 2024

Li Zewen, Zhong Wenfang, Gao Jian, Zhang Xiru, Lin Guowang, Qi Cancan, Mao Chen, Zhou Hongwei

Abstract excerpt

OBJECTIVE: This study aimed to investigate the potential causal relationship between domain-specific sedentary behaviors (including television watching, computer use, and driving) and hypertension risk in European populations. METHODS: Initially, we conducted a multivariable Cox regression analysis to evaluate the associations between domain-specific sedentary behaviors and the risk of developing hypertension...

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Genome-Wide Association Study
Hypertension
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide
Sedentary Behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38408649
DOI: 10.1016/j.ypmed.2024.107915

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