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Article

Genetic liability to sedentary behavior in relation to myocardial infarction and heart failure: A mendelian randomization study.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Nov 2022

Yang Fangkun, Huangfu Ning, Chen Songzan, Hu Teng, Qu Zihao, Wang Kai, Cui Hanbin, Xie Xiaojie

Abstract excerpt

BACKGROUND AND AIMS: Observational studies have indicated that sedentary behavior is associated with myocardial infarction (MI), heart failure (HF), and atrial fibrillation (AF). Nevertheless, whether these associations are causal remain controversial, due to confounding factors (e.g., physical activity) and reverse causality. METHODS AND RESULTS: Instrumental variables were obtained from the largest genome-wide...

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Identifiers

PMID: 36163216
DOI: 10.1016/j.numecd.2022.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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