Article
A Mendelian randomization study on causal effects of leisure sedentary behaviour on the risk of rheumatoid arthritis.
European journal of clinical investigation - 1 Mar 2023
Huang Guiwu, Cai Jiahao, Li Wenchang, Lu Qiaowei, Chen Xiong, Liao Weiming, Wu Peihui
Abstract excerpt
BACKGROUND: The causal inference between leisure sedentary behaviour (LSB) and rheumatoid arthritis (RA) is still controversial because of potential residual confounding and reverse causality. METHODS: The present study used publicly available large-scale genome-wide association studies (GWAS) of LSB (television watching, computer use, and driving) and RA to perform a two-sample Mendelian randomization (MR) study...
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