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Article

Leisure sedentary behaviour increases the risk of venous thromboembolism: a Mendelian randomisation study.

BMC cardiovascular disorders - 18 Jul 2023

Chen Liang, You Guochang, Yang Zhenmei, Shen Runnan, Zhang Rong, Zhu Dongxi, Wang Linlu, Lin Shen, Lv Lin, Huang Kai

Abstract excerpt

BACKGROUND: Venous thromboembolism (VTE) is a substantial contributor to the global burden of disease. Observational studies have suggested that leisure sedentary behaviours (LSB) are related to the risk of VTE; however, the causal role of LSB in VTE remains unclear. METHODS: Using data obtained from genome-wide association studies in the UK Biobank (N = 422,218), we identified 84, 21, and 4 single nucleotide...

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Identifiers

PMID: 37464328
DOI: 10.1186/s12872-023-03395-5
PMCID: PMC10354998

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