Association of leisure sedentary behavior and physical activity with the risk of nonalcoholic fatty liver disease: a two-sample Mendelian randomization study

Abstract excerpt

Introduction Previous observational studies have demonstrated the relationship between leisure sedentary behavior, physical activity, and nonalcoholic liver disease (NAFLD). However, whether these associations are causal or confounding factors remains unclear. Methods Pooled genetic data from the UK Biobank and other large genome-wide association studies (GWAS) were used to extract instrumental variables...

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