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Cardiac Myosin Binding Protein-C Mutations in Families With Hypertrophic Cardiomyopathy

21 Jan 2012

Abstract excerpt

BACKGROUND: Small selected cohort studies suggest that mutations in the cardiac myosin binding protein-C (MYBPC3) gene cause late-onset, clinically benign hypertrophic cardiomyopathy (HCM). The aim of this study was to test this hypothesis in a large series of families with HCM associated with MYBPC3 mutations. METHODS AND RESULTS: The initial study population comprised 57 probands with 42 mutations (26 [61.9%]...

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PMID: 22267749
DOI: 10.1161/circgenetics.111.960831

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Cardiac Myosin Binding Protein-C Mutations in Families With Hypertrophic CardiomyopathyPMID 22267749Read ↗

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