Article
Genetics of height and risk of atrial fibrillation: A Mendelian randomization study.
PLoS medicine - 1 Oct 2020
Levin Michael G, Judy Renae, Gill Dipender, Vujkovic Marijana, Verma Shefali S, Bradford Yuki, Ritchie Marylyn D, Hyman Matthew C, Nazarian Saman, Rader Daniel J, Voight Benjamin F, Damrauer Scott M
Abstract excerpt
BACKGROUND: Observational studies have identified height as a strong risk factor for atrial fibrillation, but this finding may be limited by residual confounding. We aimed to examine genetic variation in height within the Mendelian randomization (MR) framework to determine whether height has a causal effect on risk of atrial fibrillation. METHODS AND FINDINGS: In summary-level analyses, MR was performed using...
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