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Transgenerational effects of paternal exposures: the role of germline de novo mutations

23 Feb 2024

Abstract excerpt

Germline de novo mutations (DNMs) refer to spontaneous mutations arising during gametogenesis, resulting in genetic changes within germ cells that are subsequently transmitted to the next generation. While the impact of maternal exposures on germline DNMs has been extensively studied, more recent studies have begun to highlight the increasing importance of the effects of paternal factors. In this review, we have...

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PMID: 38396220
DOI: 10.1111/andr.13609

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