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Single cell-transcriptomic analysis informs the lncRNA landscape in metastatic castration resistant prostate cancer

23 Feb 2024

Abstract excerpt

Metastatic castration-resistant prostate cancer (mCRPC) is a lethal form of prostate cancer. Although long-noncoding RNAs (lncRNAs) have been implicated in mCRPC, past studies have relied on bulk sequencing methods with low depth and lack of single-cell resolution. Hence, we performed a lncRNA-focused analysis of single-cell RNA-sequencing data (n = 14) from mCRPC biopsies followed by integration with bulk...

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PMID: 38396008
DOI: 10.1038/s41525-024-00401-3

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