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Article

Association of RNF43 Genetic Alterations With BRAFV600E and MSIhigh in Colorectal Cancer.

JCO precision oncology - 1 Feb 2024

Vogel Arndt, Murugesan Karthikeyan, Kendre Gajanan, Quintanilha Julia C F, Ross Jeffrey S, Brummer Tilman, Saborowski Anna

Abstract excerpt

PURPOSE: Recent studies have provided evidence for a predictive value of RNF43 genetic alterations (GAs) as biomarkers for targeted therapies in microsatellite-stable (MSS) colorectal cancer (CRC). These data have the potential to prioritize treatment strategies in patients with BRAFV600E-mutant CRC and help to identify a subgroup that is more likely to derive benefit versus those patients for whom alternative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38394466
DOI: 10.1200/PO.23.00411

Genes

RNF43
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Association of RNF43 Genetic Alterations With BRAFV600E and MSIhigh in Colorectal Cancer.PMID 38394466Read ↗

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