Article
The possible effects of the MTOR polymorphisms on preeclampsia susceptibility, severity, and onset: a case-control study and in silico analysis.
Molecular biology reports - 23 Feb 2024
Rezaei Mahnaz, Ghasemi Marzieh, Saravani Mohsen, Ghahghayi Fatemeh, Shahraki-Ghadim Hossein, Salimi Saeedeh
Abstract excerpt
BACKGROUND: Preeclampsia (PE) is a gestational complication with developed hypertension and proteinuria. Evidence showed the role of mTOR in various cellular processes. Therefore, this study aimed to evaluate the effects of MTOR polymorphisms on susceptibility, severity, and onset of Preeclampsia (PE). METHODS AND RESULTS: A total of 250 PE pregnant women and 258 age-matched control subjects were recruited in...
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