Article
A single nucleotide polymorphism in the MTOR gene is associated with recurrent spontaneous abortion in the Chinese female population.
Systems biology in reproductive medicine - 1 Jan 2015
Xiang Huifen, Liu Shengnan, Zong Chen, Li Zelian, Liu Yunyun, Ma Xu, Cao Yunxia
Abstract excerpt
Recurrent spontaneous abortion (RSA) is a multi-factor disease. The mammalian target of the the rapamycin (MTOR) gene has been reported to be involved in mouse embryo development and regulates the proliferation of embryonic stem cells. Our study explored the relationship between the single nucleotide polymorphism (SNP) rs17027478 in the promoter region of MTOR gene and the development of RSA. A total of 306...
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