Article
Genetic variants in the mTOR pathway with renal cancer risk and subtypes in East Indian population.
Urologia - 1 May 2024
Malakar Subhajit, Chatterjee Srilagna, Das Madhusudhan, Pal Dilip Kumar
Abstract excerpt
INTRODUCTION: Renal Cell Carcinoma (RCC), which accounts for 2%-3% of all adult malignant neoplasms with a male-to-female predominance of 1.9 to 1 with typical presentation between 55 and 75 years. The phosphoinositide-3-kinase-protein kinase B/Akt (PI3KPKB/Akt) pathway is a main pathway in control of cell growth. mTOR pathway plays a key role in the pathogenesis of RCC. MATERIAL AND METHODS: Its a prospective...
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