Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PSME2 offers value as a biomarker of M1 macrophage infiltration in pan-cancer and inhibits osteosarcoma malignant phenotypes.

International journal of biological sciences - 1 Jan 2024

Li Ruoqi, Yan Lei, Jiu Jingwei, Liu Haifeng, Li Dijun, Li Xiaoke, Zhang Jing, Li Songyan, Fan Zijuan, Lv Zhi, Zhu Yuanyuan, Wang Bin

Abstract excerpt

A growing number of studies have revealed an association between proteasome activator complex subunit 2 (PSME2) and the progression of various forms of cancer. However, the effect of PSME2 on osteosarcoma progression is unknown. Pan-cancer analyses focused on the immunological activity and prognostic relevance of PSME2 have yet to be conducted. The Cancer Genome Atlas and Genome-Tissue Expression databases were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Bone Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferroptosis and cancer prognosis

Share to Macrophages

Share to Osteosarcoma

Share to Phenotype

Share to Proteasome Endopeptidase Complex

Share to Ubiquitin and proteasome pathways

Source

Open in PubMed Open full text

Identifiers

PMID: 38385075
DOI: 10.7150/ijbs.90226
PMCID: PMC10878157

Genes

PSME2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PSME2 offers value as a biomarker of M1 macrophage infiltration in pan-cancer and inhibits osteosarcoma malignant phenotypes.PMID 38385075Read ↗

Multi-omics pan-cancer analyses identify MCM4 as a promising prognostic and diagnostic biomarkerSemantic proximity Read ↗

Identification of EXO1 as a potential biomarker associated with prognosis and tumor immune microenvironment for specific human cancers.Semantic proximity Read ↗

Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-CancerSemantic proximity Read ↗

SKP2 Knockout in Rb1/p53–Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable PrognosisSemantic proximity Read ↗

PKM2 modulates chemotherapy sensitivity by regulating autophagy and predicts the prognosis and immunity in pancancerSemantic proximity Read ↗

ESCO2's Oncogenic Role in Human Tumors: A Pan-Cancer Analysis and Experimental ValidationSemantic proximity Read ↗

Comprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers <i>Skp2</i> function in metastasis, genomic instability and immune activation and reveals additional target pathwaysSemantic proximity Read ↗

Pan-Cancer Multi-Omics Analysis of Minichromosome Maintenance Proteins (MCMs) Expression in Human CancersSemantic proximity Read ↗

WISP1 Predicts Clinical Prognosis and Is Associated With Tumor Purity, Immunocyte Infiltration, and Macrophage M2 Polarization in Pan-CancerSemantic proximity Read ↗

Expression Profile, Prognostic Value, and Therapeutic Potential of NSD2 in Pan-Cancer: A Systematic Analysis Integrating Multi-Omics DataSemantic proximity Read ↗

SKP2 knockout in Rb1/p53 deficient mouse models of osteosarcoma induces immune infiltration and drives a transcriptional program with a favorable prognosisSemantic proximity Read ↗

The Potential Impact of HNRNPA2B1 on Human Cancers Prognosis and Immune Microenvironment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.