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Article

Predicting the apolipoprotein E ε4 allele carrier status based on gray matter volumes and cognitive function.

Brain and behavior - 1 Jan 2024

Kim Hyug-Gi, Tian Yunan, Jung Sue Min, Park Soonchan, Rhee Hak Young, Ryu Chang-Woo, Jahng Geon-Ho

Abstract excerpt

BACKGROUND: Apolipoprotein E (ApoE) ε4 carriers have a higher risk of developing Alzheimer's disease (AD) and show brain atrophy and cognitive decline even before diagnosis. OBJECTIVE: To predict ApoE ε4 status using gray matter volume (GMV) obtained from magnetic resonance imaging images and demographic data with machine learning (ML) methods. METHODS: We recruited 74 participants (25 probable AD, 24 amnestic...

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Identifiers

PMID: 38376028
DOI: 10.1002/brb3.3381
PMCID: PMC10772845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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