Article
Impact of Endothelial NOS VNTR Variant on Susceptibility to Diabetic Neuropathy and Type 2 Diabetes Mellitus.
Current neurovascular research - 1 Jan 2020
Yigit Serbulent, Nursal Ayse Feyda, Uzun Suheyla, Rustemoglu Husniye, Dashatan Payam Amiri, Soylu Huseyin, Atmaca Aysegul, Rustemoglu Aydin, Kuruca Nilufer, Karakus Nevin
Abstract excerpt
PURPOSE: The aim of this study was to evaluate whether the VNTR intron 4b/4a variant in the eNOS gene is associated with type 2 diabetes mellitus (T2DM) and DPN. METHODS: A total of 598 subjects were enrolled in the study. eNOS VNTR 4b/4a variant was genotyped by polymerase chain reaction (PCR) method. RESULTS: eNOS VNTR intron 4b/4b genotype and b allele increased in patients with both DPN and T2DM compared...
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