Article
Role of the IL8 rs4073 polymorphism in central nervous system toxicity in patients receiving multidrug-resistant tuberculosis treatment.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia - 1 Jan 2024
Badamasi Ibrahim Mohammed, Muhammad Muktar, Umar Aishat Ahmad, Madugu Umm-Ayman Misbahu, Gadanya Muktar Ahmed, Aliyu Isa Abubakar, Kabir Imam Malik, Umar Ibrahim Aliyu, Johnson Ochigbo, Stanslas Johnson
Abstract excerpt
OBJECTIVE: To determine the role of the IL8 rs4073 polymorphism in predicting the risk of central nervous system (CNS) toxicity in patients receiving standard pharmacological treatment for multidrug-resistant tuberculosis (MDR-TB). METHODS: A cohort of 85 consenting MDR-TB patients receiving treatment with second-line antituberculosis drugs had their blood samples amplified for the IL8 (rs4073) gene and...
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