Article
Clinical and genetic determinants of vitamin D receptor expression in cutaneous melanoma patients.
Melanoma research - 1 Apr 2024
De Smedt Julie, Aura Claudia, Van Kelst Sofie, Janssen Laudine, Marasigan Vivien, Boecxstaens Veerle, Stas Marguerite, Bogaerts Kris, Belmans Ann, Cleynen Isabelle, Vanderschueren Dirk, Vandenberghe Katleen, Bechter Oliver, Nikkels Arjen, Strobbe Tinne, Emri Gabriella, Lambrechts Dieter, Garmyn Marjan
Abstract excerpt
Decrease of vitamin D receptor (VDR) expression is observed in melanocytic naevi and melanoma compared to normal skin. Little is known about factors influencing VDR expression in cutaneous melanoma (CM). We investigated the correlation of VDR expression in CM with 25-hydroxy vitamin D (25OHD) levels, demographic/clinical parameters, genetic variants of VDR and pathology of the primary tumor. Demographic/clinical...
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