Article
Glutathione peroxidase: fact and fiction.
Ciba Foundation symposium - 1 Jan 2000
Flohé L
Abstract excerpt
The present knowledge of glutathione (GSH) peroxidase is briefly reviewed: GSH peroxidase has a molecular weight of about 85,000, consists of four apparently-identical subunits and contains four g atom of selenium/mol. The enzyme-bound selenium can undergo a substrate-induced redox change and is obviously essential for activity. In accordance with the assumption that a selenol group is reversibly oxidized during...
Topics
- Amino Acids
- Animals
- Glutathione Peroxidase
- Humans
- Kinetics
- Lipid Metabolism
- Membrane Lipids
- Mutation
- Peroxidases
- Peroxides
- Prostaglandins
- Selenium
- Substrate Specificity