Article
Consistency between Primary Uterine Corpus Malignancies and Their Corresponding Patient-Derived Xenograft Models.
International journal of molecular sciences - 25 Jan 2024
Ueda Shoko, Tanaka Tomohito, Hirosuna Kensuke, Miyamoto Shunsuke, Murakami Hikaru, Nishie Ruri, Tsuchihashi Hiromitsu, Toji Akihiko, Morita Natsuko, Hashida Sousuke, Daimon Atsushi, Terada Shinichi, Maruoka Hiroshi, Kogata Yuhei, Taniguchi Kohei, Komura Kazumasa, Ohmichi Masahide
Abstract excerpt
Patient-derived xenograft (PDX) models retain the characteristics of tumors and are useful tools for personalized therapy and translational research. In this study, we aimed to establish PDX models for uterine corpus malignancies (UC-PDX) and analyze their similarities. Tissue fragments obtained from 92 patients with uterine corpus malignancies were transplanted subcutaneously into immunodeficient mice....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
