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Article

A preliminary study of new single polymorphisms in the T helper type 17 pathway for psoriasis in the Korean population.

Clinical and experimental immunology - 1 Feb 2017

Kim S Y, Hur M S, Choi B G, Kim M J, Lee Y W, Choe Y B, Ahn K J

Abstract excerpt

Psoriasis is a polygenic and multi-factorial disease showing ethnic differences in terms of its severity and frequency. Therapies targeting interleukin (IL)-17A, IL-17 receptor (IL-17R) and Janus kinases (JAKs) are in clinical development for the treatment of psoriasis, and their success suggests the essential role of these molecules in psoriasis. To investigate the genetic susceptibility in T helper type 17...

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Source

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Identifiers

PMID: 27774581
DOI: 10.1111/cei.12888
PMCID: PMC5217933

Genes

JAK2
JAK1
CAMP
TYK2
JAK3
STAT3
TLR7
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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