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Article

Dual Roles for Immunity in Gastrointestinal Cancers

20 Jul 2010

Abstract excerpt

Histopathologic examination reveals that most human tumors are associated with diverse immune cell infiltrates, but the roles of host reactions in disease pathogenesis and prognosis remain to be fully clarified. Recent investigations in genetically engineered murine tumor models have uncovered dual functions for immune responses during cancer development and progression. Alterations in tumor cell gene expression...

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PMID: 20644090
DOI: 10.1200/jco.2010.27.9992

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