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Spatial and single-cell analyses uncover links between ALKBH1 and tumor-associated macrophages in gastric cancer

6 Feb 2024

Abstract excerpt

BACKGROUND: AlkB homolog 1, histone H2A dioxygenase (ALKBH1), a crucial enzyme involved in RNA demethylation in humans, plays a significant role in various cellular processes. While its role in tumor progression is well-established, its specific contribution to stomach adenocarcinoma (STAD) remains elusive. This study seeks to explore the clinical and pathological relevance of ALKBH1, its impact on the tumor...

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PMID: 38317214
DOI: 10.1186/s12935-024-03232-5

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