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Article

TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Apr 2010

Tabori Uri, Shlien Adam, Baskin Berivan, Levitt Sarah, Ray Peter, Alon Noa, Hawkins Cynthia, Bouffet Eric, Pienkowska Malgorzata, Lafay-Cousin Lucie, Gozali Alexa, Zhukova Nataliya, Shane Lisa, Gonzalez Ignacio, Finlay Jonathan, Malkin David

Abstract excerpt

PURPOSE Choroid plexus carcinomas are pediatric tumors with poor survival rates and a strong, but poorly understood, association with Li-Fraumeni syndrome (LFS). Currently, with lack of biologic predictors, most children are treated with aggressive chemoradiation protocols. PATIENTS AND METHODS We established a multi-institutional tissue and clinical database, which enabled the analysis of specific alterations of...

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PMID: 20308654
DOI: 10.1200/JCO.2009.26.8169

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MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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