Article
T-cell immune profile in blood of systemic mastocytosis: Association with disease features.
Allergy - 1 Jul 2024
Pérez-Pons Alba, Teodosio Cristina, Jara-Acevedo María, Henriques Ana, Navarro-Navarro Paula, García-Montero Andrés C, Álvarez-Twose Iván, Lecrevisse Quentin, Fluxa Rafael, Sánchez-Muñoz Laura, Caldas Carolina, Pozo Julio, Martín Silvia, Sanfeliciano Teresa Contreras, Pedreira Carlos E, Botafogo Vitor, González-López Oscar, Mayado Andrea, Orfao Alberto
Abstract excerpt
BACKGROUND: Systemic mastocytosis (SM) is a heterogeneous disease characterized by an expansion of KIT-mutated mast cells (MC). KIT-mutated MC display activated features and release MC mediators that might act on the tumour microenvironment and other immune cells. Here, we investigated the distribution of lymphocyte subsets in blood of patients with distinct subtypes of SM and determined its association with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.