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Article

Long-Term Risk of Atherosclerotic Cardiovascular Disease in US Adults With the Familial Hypercholesterolemia Phenotype.

Circulation - 5 Jul 2016

Perak Amanda M, Ning Hongyan, de Ferranti Sarah D, Gooding Holly C, Wilkins John T, Lloyd-Jones Donald M

Abstract excerpt

BACKGROUND: Heterozygous familial hypercholesterolemia (FH) affects up to 1 in 200 individuals in the United States, but atherosclerotic cardiovascular disease (ASCVD) outcomes of FH in the general US population have not been described. We therefore sought to evaluate long-term coronary heart disease (CHD) and total ASCVD risks in US adults with an FH phenotype. METHODS: Using individual pooled data from 6 large...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27358432
DOI: 10.1161/CIRCULATIONAHA.116.022335
PMCID: PMC4933328

Genes

FH

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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