Article
Familial Hypercholesterolemia.
Methodist DeBakey cardiovascular journal - 1 Jan 2026
Iatan Iulia, Genest Jacques
Abstract excerpt
Familial hypercholesterolemia (FH) is a semi-dominant, autosomal, monogenic lipoprotein disorder characterized by severe elevations in low-density lipoprotein cholesterol (LDL-C) and premature atherosclerotic cardiovascular disease (ASCVD). The most common form, heterozygous FH, has an estimated prevalence of approximately 1 per 311 individuals, making it one of the most common hereditary disorders in medicine....
Read the complete abstract on PubMedTopics
- Humans
- Hyperlipoproteinemia Type II
- Genetic Predisposition to Disease
- Phenotype
- Biomarkers
- Cholesterol, LDL
- Female