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Article

Chronic osteomyelitis risk is associated with NLRP3 gene rs10754558 polymorphism in a Chinese Han Population.

BMC medical genomics - 29 Jan 2024

Qu Yu-Dun, Jiang Nan, Li Jia-Xuan, Zhang Wei, Xia Chang-Liang, Ou Shuan-Ji, Yang Yang, Ma Yun-Fei, Qi Yong, Xu Chang-Peng

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the nucleotide-binding domain leucine-rich repeat protein-3 (NLRP3) gene are reported to be linked to many inflammatory disorders. However, uncertainty persists over the associations between these SNPs and susceptibilities to chronic osteomyelitis (COM). This study aimed to investigate potential relationships between NLRP3 gene SNPs and the risks of developing...

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Identifiers

PMID: 38287380
DOI: 10.1186/s12920-024-01799-6
PMCID: PMC10823619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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