Article
Advances in the Diagnosis and Treatment of Advanced Non-Small-Cell Lung Cancer With EGFR Exon 20 Insertion Mutation.
Clinical lung cancer - 1 Mar 2024
Liu Jingwen, Xiang Yan, Fang Tingwen, Zeng Lulin, Sun Ao, Lin Yixiang, Lu Kaihua
Abstract excerpt
The discovery of epidermal growth factor receptor (EGFR) mutations has greatly changed the clinical outlook for patients with advanced non-small-cell lung cancer (NSCLC). Unlike the most common EGFR mutations, such as exon 19 deletion (del19) and exon 21 L858R point mutation, EGFR exon 20 insertion mutation (EGFR ex20ins) is a rare mutation of EGFR. Due to its structural specificity, it exhibits primary...
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