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Article

Race, Genotype, and Prognosis in Black Patients With Transthyretin Cardiac Amyloidosis.

The American journal of cardiology - 1 Apr 2024

Khedraki Rola, Saef Joshua, Martens Pieter, Martyn Trejeeve, Sul Lidiya, Hachamovitch Rory, Ives Lauren, Estep Jerry D, Tang W H Wilson, Hanna Mazen

Abstract excerpt

Previous studies suggest worse outcomes in patients with variant transthyretin cardiac amyloidosis (ATTR-CA) because of valine-to-isoleucine substitution at Position 122 (V122I) (ATTRv-CA) compared with patients with wild-type (WT) disease (ATTRwt-CA). Given V122I is almost exclusively found in Black patients, it is unclear if this is attributable to the biology of genotype or racial differences. Patients with...

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PMID: 38278432
DOI: 10.1016/j.amjcard.2024.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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