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Single-cell RNA sequencing reveals hub genes of myocardial infarction-associated endothelial cells

24 Jan 2024

Abstract excerpt

BACKGROUND: Myocardial infarction (MI) is a cardiovascular disease that seriously threatens human health. Dysangiogenesis of endothelial cells (ECs) primarily inhibits recovery from MI, but the specific mechanism remains to be further elucidated. METHODS: In this study, the single-cell RNA-sequencing data from both MI and Sham mice were analyzed by the Seurat Package (3.2.2). The number of ECs in MI and Sham...

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PMID: 38267885
DOI: 10.1186/s12872-024-03727-z

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