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Single-cell transcriptomics and machine learning reveal RNF144B and C5AR1 as immune-related biomarkers and therapeutic targets in myocardial infarction

2025-09-06

Abstract excerpt

<h4>Background</h4> Myocardial infarction (MI) is a life-threatening cardiovascular disease characterized by high morbidity and mortality. Although advances in clinical management have improved patient outcomes, early diagnosis and effective immunomodulatory therapies remain limited. <h4>Methods</h4> In this study, we integrated multiple transcriptomic datasets and applied machine learning approaches, including...

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Literature Corpus work
68ba8673-cdb5-528e-a48a-f6c1f5c5a6de
DOI
10.1101/2025.09.03.673891
Open publication

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Single-cell transcriptomics and machine learning reveal RNF144B and C5AR1 as immune-related biomarkers and therapeutic targets in myocardial infarctionDOI 10.1101/2025.09.03.673891
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