Article
Using simulated microhaplotype genotyping data to evaluate the value of machine learning algorithms for inferring DNA mixture contributor numbers.
Forensic science international. Genetics - 1 Mar 2024
Wang Haoyu, Zhu Qiang, Huang Yuguo, Cao Yueyan, Hu Yuhan, Wei Yifan, Wang Yuting, Hou Tingyun, Shan Tiantian, Dai Xuan, Zhang Xiaokang, Wang Yufang, Zhang Ji
Abstract excerpt
Inferring the number of contributors (NoC) is a crucial step in interpreting DNA mixtures, as it directly affects the accuracy of the likelihood ratio calculation and the assessment of evidence strength. However, obtaining the correct NoC in complex DNA mixtures remains challenging due to the high degree of allele sharing and dropout. This study aimed to analyze the impact of allele sharing and dropout on NoC...
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